Skip to main content

Advertisement

SpringerLink
Log in

SPECT/CT in pediatric patient management

  • Review Article
  • Published:
European Journal of Nuclear Medicine and Molecular Imaging Aims and scope Submit manuscript

Abstract

Hybrid SPECT/CT imaging is becoming the standard of care in pediatric imaging. Indications are mainly for oncologic imaging including mIBG scintigraphy for neuroblastoma and I-123 post surgical imaging of children with thyroid carcinoma, bone scintigraphy for back pain, children referred from sports medicine and neurodevelopmentally delayed children presenting with pain symptoms. The studies provide improved diagnostic accuracy, and oncologic imaging that includes optimized CT as part of the SPECT/CT study may decrease the number of studies and sedation procedures an individual child may need. The studies, however, must be tailored on an individual basis as the addition of the CT study can increase exposure to the child and should only be performed after appropriate justification and with adherence to optimized low dose pediatric protocols.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11

Similar content being viewed by others

References

  1. Fahey FH, Treves ST, Adelstein SJ. Minimizing and communicating radiation risk in pediatric nuclear medicine. J Nucl Med Off Publ So Nucl Med. 2011;52(8):1240–51. doi:10.2967/jnumed.109.069609.

    Google Scholar 

  2. Gelfand MJ. Dose reduction in pediatric hybrid and planar imaging. Q J Nucl Med Mol Imaging Off Publ Ital Assoc Nucl Med Int Assoc Radiopharm Sec So. 2010;54(4):379–88.

    CAS  Google Scholar 

  3. Gelfand MJ, Parisi MT, Treves ST. Pediatric Nuclear Medicine Dose Reduction W. Pediatric radiopharmaceutical administered doses: 2010 North American consensus guidelines. J Nucl Med Off Publ So Nucl Med. 2011;52(2):318–22.

    Google Scholar 

  4. Lassmann M, Biassoni L, Monsieurs M, Franzius C, Jacobs F. The new EANM paediatric dosage card. Eur J Nucl Med Mol Imaging. 2007;34(5):796–8. doi:10.1007/s00259-007-0370-0.

    Article  CAS  PubMed  Google Scholar 

  5. Goske MJ, Applegate KE, Boylan J, Butler PF, Callahan MJ, Coley BD, et al. The ‘Image Gently” campaign: increasing CT radiation dose awareness through a national education and awareness program. Pediatr Radiol. 2008;38(3):265–9. doi:10.1007/s00247-007-0743-3.

    Article  PubMed  Google Scholar 

  6. Goske MJ, Applegate KE, Bulas D, Butler PF, Callahan MJ, Don S, et al. Image Gently 5 years later: what goals remain to be accomplished in radiation protection for children? AJR Am J Roentgenol. 2012;199(3):477–9. doi:10.2214/AJR.12.9655.

    Article  PubMed  Google Scholar 

  7. Jafari ME, Daus AM. Applying Image Gently SM and Image Wisely SM in nuclear medicine. Health Phys. 2013;104(2 Suppl 1):S31–6. doi:10.1097/HP.0b013e3182764cd8.

    Article  CAS  PubMed  Google Scholar 

  8. Kim HY, Gelfand MJ, Sharp SE. SPECT/CT imaging in children with papillary thyroid carcinoma. Pediatr Radiol. 2011;41(8):1008–12. doi:10.1007/s00247-011-2039-x.

    Article  PubMed  Google Scholar 

  9. Chakera AH, Hesse B, Burak Z, Ballinger JR, Britten A, Caraco C, et al. EANM-EORTC general recommendations for sentinel node diagnostics in melanoma. Eur J Nucl Med Mol Imaging. 2009;36(10):1713–42. doi:10.1007/s00259-009-1228-4.

    Article  CAS  PubMed  Google Scholar 

  10. Klode J, Poeppel T, Boy C, Mueller S, Schadendorf D, Korber A, et al. Advantages of preoperative hybrid SPECT/CT in detection of sentinel lymph nodes in cutaneous head and neck malignancies. J Eur Acad Dermatol Venereol. 2011;25(10):1213–21. doi:10.1111/j.1468-3083.2010.03954.x.

    Article  CAS  PubMed  Google Scholar 

  11. Stoffels I, Boy C, Poppel T, Kuhn J, Klotgen K, Dissemond J, et al. Association between sentinel lymph node excision with or without preoperative SPECT/CT and metastatic node detection and disease-free survival in melanoma. J Am Med Assoc. 2012;308(10):1007–14. doi:10.1001/2012.jama.11030.

    Article  CAS  Google Scholar 

  12. Connolly LP, d’Hemecourt PA, Connolly SA, Drubach LA, Micheli LJ, Treves ST. Skeletal scintigraphy of young patients with low-back pain and a lumbosacral transitional vertebra. J Nucl Med Off Publ So Nucl Med. 2003;44(6):909–14.

    Google Scholar 

  13. Miller R, Beck NA, Sampson NR, Zhu X, Flynn JM, Drummond D. Imaging modalities for low back pain in children: a review of spondyloysis and undiagnosed mechanical back pain. J Pediatr Orthop. 2013;33(3):282–8. doi:10.1097/BPO.0b013e318287fffb.

    Article  PubMed  Google Scholar 

  14. Campbell RS, Grainger AJ, Hide IG, Papastefanou S, Greenough CG. Juvenile spondylolysis: a comparative analysis of CT, SPECT and MRI. Skelet Radiol. 2005;34(2):63–73. doi:10.1007/s00256-004-0878-3.

    Article  CAS  Google Scholar 

  15. Gregory PL, Batt ME, Kerslake RW, Scammell BE, Webb JF. The value of combining single photon emission computerised tomography and computerised tomography in the investigation of spondylolysis. Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deformity Soc Eur Sect Cervical Spine Res Soc. 2004;13(6):503–9. doi:10.1007/s00586-004-0696-2.

    Article  CAS  Google Scholar 

  16. Gregory PL, Batt ME, Kerslake RW, Webb JK. Single photon emission computerized tomography and reverse gantry computerized tomography findings in patients with back pain investigated for spondylolysis. Clin J Sport Med Off J Can Acad Sport Med. 2005;15(2):79–86.

    Article  Google Scholar 

  17. Kobayashi A, Kobayashi T, Kato K, Higuchi H, Takagishi K. Diagnosis of radiographically occult lumbar spondylolysis in young athletes by magnetic resonance imaging. Am J Sports Med. 2013;41(1):169–76. doi:10.1177/0363546512464946.

    Article  PubMed  Google Scholar 

  18. Yang J, Servaes S, Edwards K, Zhuang H. Prevalence of stress reaction in the pars interarticularis in pediatric patients with new-onset lower back pain. Clin Nucl Med. 2013;38(2):110–4. doi:10.1097/RLU.0b013e318279fd23.

    Article  PubMed  Google Scholar 

  19. Van der Wall H, Fogelman I. Scintigraphy of benign bone disease. Semin Musculoskelet Radiol. 2007;11(4):281–300. doi:10.1055/s-2008-1060332.

    Article  PubMed  Google Scholar 

  20. Pripatnanont P, Vittayakittipong P, Markmanee U, Thongmak S, Yipintsoi T. The use of SPECT to evaluate growth cessation of the mandible in unilateral condylar hyperplasia. Int J Oral Maxillofac Surg. 2005;34(4):364–8. doi:10.1016/j.ijom.2004.11.002.

    Article  CAS  PubMed  Google Scholar 

  21. Brandao SC, Gondra Lde A, Viana RA, Andrade LR, Brandt CT. Late splenosis evaluation after autoimplantation of spleen morsels in major omentum in hepatosplenic schistosomiasis patients using SPECT/CT imaging. Clin Nucl Med. 2012;37(4):372–3. doi:10.1097/RLU.0b013e31823ea497.

    Article  PubMed  Google Scholar 

  22. Jain A, Chauhan M, Pandit A, Kumar R, Sharma A. Promising role of single photon emission computed tomography/computed tomography in Meckel’s scan. Indian J Nucl Med Off J Soc Nucl Med India. 2012;27(3):196–8. doi:10.4103/0972-3919.112738.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Pediatric Radiologist and Nuclear Medicine Physician, Division of Nuclear Medicine Department of Radiology, British Columbia Children’s Hospital, University of British Columbia, 4480 Oak Street, Vancouver, British Columbia, Canada, V6H3V4

    Helen R. Nadel

Authors
  1. Helen R. Nadel
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Helen R. Nadel.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nadel, H.R. SPECT/CT in pediatric patient management. Eur J Nucl Med Mol Imaging 41 (Suppl 1), 104–114 (2014). https://doi.org/10.1007/s00259-014-2697-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00259-014-2697-7

Keywords

Search

Navigation