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EANM 2012 guidelines for radionuclide imaging of phaeochromocytoma and paraganglioma

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European Journal of Nuclear Medicine and Molecular Imaging Aims and scope Submit manuscript

Abstract

Purpose

Radionuclide imaging of phaeochromocytomas (PCCs) and paragangliomas (PGLs) involves various functional imaging techniques and approaches for accurate diagnosis, staging and tumour characterization. The purpose of the present guidelines is to assist nuclear medicine practitioners in performing, interpreting and reporting the results of the currently available SPECT and PET imaging approaches. These guidelines are intended to present information specifically adapted to European practice.

Methods

Guidelines from related fields, issued by the European Association of Nuclear Medicine and the Society of Nuclear Medicine, were taken into consideration and are partially integrated within this text. The same was applied to the relevant literature, and the final result was discussed with leading experts involved in the management of patients with PCC/PGL. The information provided should be viewed in the context of local conditions, laws and regulations.

Conclusion

Although several radionuclide imaging modalities are considered herein, considerable focus is given to PET imaging which offers high sensitivity targeted molecular imaging approaches.

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Authors and Affiliations

  1. Department of Nuclear Medicine, La Timone University Hospital, CERIMED, Aix-Marseille University, France

    David Taïeb

  2. Department of Endocrinology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

    Henri J. Timmers

  3. Department of Nuclear Medicine, Haut-Lévêque Hospital, University of Bordeaux-2, Bordeaux, France

    Elif Hindié

  4. Department of Radiopharmacy, La Timone University Hospital, CERIMED, Aix-Marseille University, France

    Benjamin A. Guillet

  5. Preventive Medicine Unit, Department of Medicine, University Medical Center, Albert-Ludwigs-University, Freiburg, Germany

    Hartmut P. Neumann

  6. Department of Surgery and Center of Minimally Invasive Surgery, Kliniken Essen-Mitte, Essen, Germany

    Martin K. Walz

  7. Endocrinology Unit, Department of Medical and Surgical Sciences, University Hospital of Padova, Padova, Italy

    Giuseppe Opocher

  8. Department of Internal Medicine, Section Endocrinology, Erasmus MC, Rotterdam, The Netherlands

    Wouter W. de Herder

  9. Department of Otorhinolaryngology – Head and Neck Surgery, University of Freiburg, Freiburg, Germany

    Carsten C. Boedeker

  10. Department of Pathology, Josephine Nefkens Institute, Erasmus MC, University Medical Center Rotterdam, Rotterdamn, The Netherlands

    Ronald R. de Krijger

  11. Department of Nuclear Medicine, Istituto Clinico Humanitas, Rozzano, MI, Italy

    Arturo Chiti

  12. Department of Nuclear Medicine, Hammersmith Hospital, London, UK

    Adil Al-Nahhas

  13. Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institutes of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA

    Karel Pacak

  14. Department of Nuclear Medicine, PET/CT Centre, Radiology, Neuroradiology, Medical Physics, ‘Santa Maria della Misericordia’ Hospital, Rovigo, Italy

    Domenico Rubello

Authors
  1. David Taïeb
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  2. Henri J. Timmers
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  3. Elif Hindié
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  4. Benjamin A. Guillet
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  5. Hartmut P. Neumann
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  6. Martin K. Walz
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  7. Giuseppe Opocher
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  8. Wouter W. de Herder
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  9. Carsten C. Boedeker
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  10. Ronald R. de Krijger
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  11. Arturo Chiti
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  12. Adil Al-Nahhas
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  13. Karel Pacak
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  14. Domenico Rubello
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Corresponding authors

Correspondence to David Taïeb or Domenico Rubello.

Additional information

Purpose

The purpose of these guidelines is to assist nuclear medicine practitioners in:

1. Understanding the role and challenges of radionuclide imaging of phaeochromocytomas/paragangliomas.

2. Providing practical information for performing different imaging procedures for these tumours.

3. Providing an algorithm for selecting the most appropriate imaging procedure in each specific clinical situation to localize and characterize these tumours.

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Taïeb, D., Timmers, H.J., Hindié, E. et al. EANM 2012 guidelines for radionuclide imaging of phaeochromocytoma and paraganglioma. Eur J Nucl Med Mol Imaging 39, 1977–1995 (2012). https://doi.org/10.1007/s00259-012-2215-8

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  • DOI: https://doi.org/10.1007/s00259-012-2215-8

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