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Integration of genomics, proteomics, and imaging for cardiac stem cell therapy

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Abstract

Cardiac stem cell therapy is beginning to mature as a valid treatment for heart disease. As more clinical trials utilizing stem cells emerge, it is imperative to establish the mechanisms by which stem cells confer benefit in cardiac diseases. In this paper, we review three methods—molecular cellular imaging, gene expression profiling, and proteomic analysis—that can be integrated to provide further insights into the role of this emerging therapy.

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Authors and Affiliations

  1. Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA, USA

    Hyung J. Chun & Joseph C. Wu

  2. Molecular Imaging Program at Stanford, Department of Radiology, Stanford University School of Medicine, 300 Pasteur Drive, Edwards Building, Room R-354, Stanford, CA, 94305-5324, USA

    Kitch O. Wilson, Mei Huang & Joseph C. Wu

Authors
  1. Hyung J. Chun
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  2. Kitch O. Wilson
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  3. Mei Huang
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  4. Joseph C. Wu
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Correspondence to Joseph C. Wu.

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Chun, H.J., Wilson, K.O., Huang, M. et al. Integration of genomics, proteomics, and imaging for cardiac stem cell therapy. Eur J Nucl Med Mol Imaging 34 (Suppl 1), 20–26 (2007). https://doi.org/10.1007/s00259-007-0437-y

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  • DOI: https://doi.org/10.1007/s00259-007-0437-y

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