Skip to main content
Log in

Issues specific to implementing PET–CT for pediatric oncology: what we have learned along the way

  • Minisymposium
  • Published:
Pediatric Radiology Aims and scope Submit manuscript

Abstract

In parallel with the expansion of PET imaging to pediatric patients has been the technological development of merging state-of-the-art cross-sectional anatomic information (CT) with functional imaging (PET) into a single modality: PET–CT. Attending to the clinical, scheduling, and medical needs that are unique to imaging children and adolescents can be a challenge, particularly when instituting a single new modality. When that modality bridges two unique, previously independent methods—often previously located in two separate departmental divisions—the details and logistics required to set up a smoothly functioning process can be particularly difficult. This paper focuses on our experience in implementing PET–CT in a tertiary pediatric referral center.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1a, b.
Fig. 2a, b.
Fig. 3.
Fig. 4.
Fig. 5.
Fig. 6.
Fig. 7.

Similar content being viewed by others

References

  1. Antoch G, Freudenberg LS, Strattus J, et al (2002) Whole-body positron emission tomography-CT: optimized CT using oral and IV contrast materials. AJR 179:1555–1560

    Google Scholar 

  2. Dizendorf EV, Treyer V, von Schulthess GK, et al (2002) Application of oral contrast media in coregistered positron emission tomography-CT. AJR 179:477–481

    Google Scholar 

  3. Holbrook S (2002) 18-FDG PET whole-body imaging: developing an oncology protocol. Adv Imag Radiat Ther 15:9

    Google Scholar 

  4. Goerres GW, von Schulthess GK, Hany TF (2002) Positron emission tomography and PET CT of the head and neck: FDG uptake in normal anatomy, in benign lesions, and in changes resulting from treatment. AJR 179:1337-1343

    Google Scholar 

  5. Kostakiglu L, Agress H, Goldsmith SJ (2003) Clinical role of FDG PET in evaluation of cancer patients. Radiographics 23:315–340

    PubMed  Google Scholar 

  6. Daldrup-Link HE, Franzius C, Link TM, et al (2001) Whole-body imaging for detection of bone metastases in children and young adults: comparison with skeletal scintigraphy and FDG PET. AJR 177:229–236

    CAS  PubMed  Google Scholar 

  7. Hawkins DS, Rajendran JG, Conrad EU III, et al (2002) Evaluation of chemotherapy response in pediatric bone sarcomas by [F-18]-fluorodeoxy-d-glucose positron emission tomography. Cancer 94:3277–3284

    Article  CAS  PubMed  Google Scholar 

  8. Brenner W, Bohuslavizki KH, Eary JF (2003) PET imaging of osteosarcoma. J Nucl Med 44:930–942

    PubMed  Google Scholar 

  9. Bredella MA, Caputo GR, Steinback LS (2002) Value of FDG positron emission tomography in conjunction with MR imaging for evaluating therapy response in patients with musculoskeletal sarcomas. AJR 179:1145–1150

    PubMed  Google Scholar 

  10. Franzius C, Sciuk J, Daldrup-Link HE, et al (2000) PDG-PET for detection of osseous metastases from malignant primary bone tumours: comparison with bone scintigraphy. Eur J Nucl Med 27:1305–1311

    CAS  PubMed  Google Scholar 

  11. Shulkin BL, Mitchell DSA, Ungar DR, et al (1995) Neoplasms in a pediatric population: 2-[F-18]-fluoro-2-deoxy-d-glucose PET studies. Radiology 194:495–500

    CAS  PubMed  Google Scholar 

  12. Shulkin BL, Hutchinson RJ, Castle VP, et al (1996) Neuroblastoma: positron emission tomography with 2-[fluorine-18]-fluoro-2-doexy-d-glucose compared with metaiodobenzylguanidine scintigraphy. Radiology 199:743–750

    CAS  PubMed  Google Scholar 

  13. Kushner BH, Yeung HWD, Larson SM, et al (2001) Extending positron emission tomography scan utility to high-risk neuroblastoma: fluorine-18 fluorodeoxyglucose positron emission tomography as sole imaging modality in follow-up patients. J Clin Oncol 19:3397–3405

    CAS  PubMed  Google Scholar 

  14. Scharko AM, Perlman SC, Pyzalski RW, et al (2003) Whole-body positron emission tomography in patients with HIV-1 infection. Lancet 362:959–961

    Article  PubMed  Google Scholar 

  15. Iyengar S, Chin B, Margolick JB, et al (2003) Anatomical loci of HIV-associated immune activation and association with viraemia. Lancet 362:945–950

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sue C. Kaste.

Additional information

Supported in part by grants P30 CA-21765 and P01 CA-20180 from the National Cancer Institute, a Center of Excellence grant from the state of Tennessee from the National Institutes of Health, and by the American Lebanese Syrian Associated Charities (ALSAC)

CME activity Please find the CME information and questions at the end of this issue

The author(s) have no financial interest, arrangement, or affiliation to disclose in the context of this CME activity. There is nothing to disclose regarding investigational or “off-label” use of medical devices or other products, or any pharmaceutical agents

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kaste, S.C. Issues specific to implementing PET–CT for pediatric oncology: what we have learned along the way. Pediatr Radiol 34, 205–213 (2004). https://doi.org/10.1007/s00247-003-1111-6

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00247-003-1111-6

Keywords

Navigation