Abstract
PET enables not only visualization of the distribution of radiotracer, but also has ability to quantify several biomedical functions. Compartmental model is a basic idea to analyze dynamic PET data. This review describes the principle of the compartmental model and categorizes the techniques and approaches for the compartmental model according to various aspects: model design, experimental design, invasiveness, and mathematical solution. We also discussed advanced applications of the compartmental analysis with PET.
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Watabe, H., Ikoma, Y., Kimura, Y. et al. PET kinetic analysis—compartmental model. Ann Nucl Med 20, 583–588 (2006). https://doi.org/10.1007/BF02984655
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DOI: https://doi.org/10.1007/BF02984655