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Separation of99mTc from parent99Mo by solid-phase column extraction as a simple option for a new99mTc generator concept

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Abstract

Evidence is obtained to show that the liquidliquid extraction separation of99mTc from99Mo with methyl ethyl ketone, methyl propyl ketone and methyl isobutyl ketone can be transformed into a solid-phase column extraction procedure. The aqueous alkaline99molybdate solution is immobilized on a column of a granular large-pore diatomaceous earch support, which is the neluted with the abovementioned extractants. Rapid and clean separation of99mTc can be with all three solvents. The99mTc can be back-extracted from the organic phase on a column filled with distilled water /or saline/ loaded granular diatomaceous earth /Extrelut®/. The possibility of using the abovementioned procedure as a basis for a new99mTc/99Mo generator concept is envisaged.

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Authors and Affiliations

  1. Institute of Inorganic and Analytical Chemistry, L. Eötvös University, P.O.Box 123, H-1443, Budapest, Hungary

    T. Braun

  2. Department of Chemistry, Tohoku University, Sendai, Japan

    H. Imura & N. Suzuki

Authors
  1. T. Braun
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  2. H. Imura
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  3. N. Suzuki
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Braun, T., Imura, H. & Suzuki, N. Separation of99mTc from parent99Mo by solid-phase column extraction as a simple option for a new99mTc generator concept. Journal of Radioanalytical and Nuclear Chemistry Letters 119, 315–325 (1987). https://doi.org/10.1007/BF02162611

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  • DOI: https://doi.org/10.1007/BF02162611

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