Abstract
Gallium-67-citrate scanning was performed in 9 patients with ulcerative colitis. In all patients there was good correlation between the regional uptake of gallium and the extent and activity of disease. In 2 patients the scans were positive during an acute exacerbation and reverted to normal or near normal during clinical remission. In one patient in whom the colon was resected because of toxic dilatation, good correlation was found between pathologic and scintigraphic examinations. During the acute attack of ulcerative colitis, when colonoscopy or barium enema may be contraindicated, gallium scanning may be a noninvasive means of assessing the extent of colonic involvement. It may also be an alternative means of following the clinical course of the disease.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Wilks S.: Morbid appearances in the intestines of Miss Bankes.Med Times Gazette 40:264–265, 1859
Royal Society of Medicine: Statistics of ulcerative colitis from London hospitals.Proc R Soc Med 2:100, 1909
Welin S, Brahme F: The double contrast method in ulcerative colitis.Acta Radiol (Scand) 55:257–271, 1961
Fennessey JJ, Sparberg M, Kirsner JB: Early roentgen manifestations of mild ulcerative colitis and proctitis.Radiology 87:848–858, 1966
Simpkins KC, Stevenson GW: The modified Mälmo double contrast barium enema in colitis.Br J Radiol 45:486–492, 1972
Laufer I: The radiologic demonstration of early changes in ulcerative colitis by double contrast technique.J Can Assoc Radiol 26:116–121, 1975
Laufer I, Mullens JE, Hamilton J: Correlation of endoscopy and double contrast radiography in the early stages of ulcerative and granulomatous colitis.Radiology 118:1–5, 1976
Laufer I: The double contrast enema: myths and misconceptions.Gastrointest Radiol 1:19–31, 1976
Kaplan LR, Griep RJ, Schuffler MD, Silliman R: Gallium-67 scanning at six hours in active inflammatory bowel disease: case report.J Nucl Med 18:448–449, 1977
Lavender JP, Lowe J, Barker JR, Burn JI, Chaudhri MA: Gallium 67 citrate scanning in neoplastic and inflammatory lesions.Br J Radiol 44:361–366, 1971
Hopkins GB, Kan M, Mende CW: Early67Ga scintigraphy for the localization of abdominal abscesses.J Nucl Med 16:990–992, 1975
Tedesco FJ, Coleman RE, Siegal BA: Gallium citrate Ga67 accumulation in pseudomembranous colitis.JAMA 235:59–60, 1976
Perkins PJ: Evaluation of bowel activity in early67Ga imaging of the abdomen.J Nucl Med 19:733, 1978 (abst)
Goldfarb CR, Leiman PM: Gallium activity in the normal colon at 6 hours: a case report.Clin Nucl Med 3:372–373, 1978
Burleson RL, Johnson MC, Head H: Scintigraphic demonstration of experimental abscesses with intravenous67Ga-citrate and67Ga labelled blood leukocytes.Ann Surg 178:446–452, 1973
Gelrud LG, Arseneau JC, Milder MS, Kramer RJ, Swann SJ, Canellos GP Johnston GS: The kinetics of67Gallium incorporation into inflammatory lesions: experimental and clinical studies.J Lab Clin Med 83:489–495, 1974
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Jones, B., Abbruzzese, A.A., Hill, T.C. et al. Gallium-67-citrate scintigraphy in ulcerative colitis. Gastrointest Radiol 5, 267–272 (1980). https://doi.org/10.1007/BF01888644
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01888644