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Gadolinium DTPA enhanced magnetic resonance imaging in acute head injury

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Summary

We studied the effect of contrast enhancement on magnetic resonance imaging (Gadolinium DTPA Magnetic Resonance) in 10 patients with a recent head injury. The use of contrast did not increase the number of traumatic lesions identified and we did not detect evidence of altered blood brain barrier permeability in any of the 7 patients, who had a total of 27 lesions, imaged between one and 4 days after injury. Enhancement was found in each of 3 patients imaged 6 or more days after injury. These findings suggest that traumatic cortical and intraparenchymal lesions are not associated with increased cerebrovascular permeability within the first 96 hours of a head injury.

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Author notes

  1. D. A. Lang

    Present address: Department of Neurosurgery, Wessex Neurological Centre, Southampton General Hospital, S09 4X, Southampton, UK

Authors and Affiliations

  1. Institute of Neurological Sciences, University Department of Neurosurgery, Southern General Hospital, Glasgow, UK

    D. A. Lang, D. M. Hadley, G. M. Teasdale, P. Macpherson & E. Teasdale

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  1. D. A. Lang
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  2. D. M. Hadley
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  3. G. M. Teasdale
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  4. P. Macpherson
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  5. E. Teasdale
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Lang, D.A., Hadley, D.M., Teasdale, G.M. et al. Gadolinium DTPA enhanced magnetic resonance imaging in acute head injury. Acta neurochir 109, 5–11 (1991). https://doi.org/10.1007/BF01405689

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