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Gastric emptying of varying meal weight and composition in man

Evaluation by dual liquid- and solid-phase isotopic method

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Abstract

Ten subjects were given self-selected filling meals (mean weight=1692 g) and meals of 900 and 300 g. The three meals varied in composition and total kcal. Solid and liquid phase gastric emptying was evaluated using99mTc-sulfur colloid-labeled chicken liver and [111In]DTPA, and emptying was quantitated using the geometric mean of the anterior and posterior counts. Emptying of the solid-phase marker was linear; mean half-emptying times were 277 min, 146 min, and 77 min for the filling, 900-g, and 300-g meals, respectively. Emptying of the liquid-phase marker was curvilinear, mean half-emptying times were 178 min, 81 min, and 40 min, for the filling, 900-g, and 300-g meals, respectively. Thus, meals of larger weight and kcal content were associated with longer emptying times for both solids and liquids.

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Authors and Affiliations

  1. Departments of Medicine and Radiology, University of Utah Medical Center, 84148, Salt Lake City, Utah

    J. G. Moore MD, P. E. Christian BS & R. E. Coleman MD

  2. Veterans Administration Medical Center, 500 Foothill Drive, 84148, Salt Lake City, Utah

    J. G. Moore MD, P. E. Christian BS & R. E. Coleman MD

Authors
  1. J. G. Moore MD
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  2. P. E. Christian BS
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  3. R. E. Coleman MD
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Moore, J.G., Christian, P.E. & Coleman, R.E. Gastric emptying of varying meal weight and composition in man. Digest Dis Sci 26, 16–22 (1981). https://doi.org/10.1007/BF01307971

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  • DOI: https://doi.org/10.1007/BF01307971

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