Abstract
The worst case radiation dose to tissue due to inadvertent intravenous injection of a radiopharmaceutical was estimated for the most commonly utilised radioisotopes. The probability of radiation injury induction was examined for the various radionuclides considering the maximal specific activity values encountered in diagnostic practice. A possible approach to the management of incidents involving extravasal activity deposition is discussed.
References
Bronskill, Michael J (1983) Radiation dose estimates for interstitial radiocolloid lymphoscintigraphy. Semin Nucl Med XIII:20–25
Castronovo FP, McKusick KA, Strauss HW (1984) Dosimetric implications of the infiltrated injection. J Nucl Med 25:40
Dillman LT, Von der Lage FC (1975) NM/MIRD Pamphlet No. 10: Radionuclide decay schemes and Nuclear Parameters for use in radiation dose estimation. Society of Nuclear Medicine, New York
European Joint Committee on Radiopharmaceuticals of the European Society of Nuclear Medicine and the Society of Nuclear Medicine Europe (1985) Injection of Radiopharmaceuticals (Newsletter). Nucl Med Commun 6:669–674
Larson DL (1985) What is the apropriate management of tissue extravasation by antitumour agents. Plast Reconstr Surg 75:397–402
Larson ML, Carrasquilloo JA, McGuffin RW, Krohn KA, Ferens JM, Hill LD, Beaumier PL, Reynolds JC, Hellstrom KE, Hellstrom I (1985) Use of I-131 labeled Murine Fab against a High Molecular weight antigen of human melanoma: preliminary experience. Radiology 155:487–492
Nass Harold W (1977) New TL-201 Nuclear decay data (Letter to the editor). J Nucl Med 18:1047–1048
Piers DA, Driessen LHHM, Beekhuis H (1985) Radiation ulcer due to inadvertent extravasal injection of Tl-201. Dosimetric considerations. (Poster). European Nuclear Medicine Congress, London
Reinisch John F, Puckett Charles L (1984) Management of radiation wounds. Surg Clin North Am 64:795
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Shapiro, B., Pillay, M. & Cox, P.H. Dosimetric consequences of interstitial extravasation following IV administration of a radiopharmaceutical. Eur J Nucl Med 12, 522–523 (1987). https://doi.org/10.1007/BF00620478
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DOI: https://doi.org/10.1007/BF00620478