Biochemical and Biophysical Research Communications
Regular ArticleProteome Analysis of Hepatocellular Carcinoma☆
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2018, GastroenterologyCitation Excerpt :Furthermore, increased levels of LMNB1 associated with larger tumors, increased number of tumor foci, and more advanced disease; LMNB1 mRNA was increased in plasma from patients with HCC compared to individuals without HCC.51 LMNB1 might therefore serve as a prognostic marker for patients with early- and late-stage HCC.83,84 Levels of lamin-associated and other nuclear proteins have also been examined in gastrointestinal tumors.
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Abbreviations used: HCC, hepatocellular carcinoma; 2-DE, two-dimensional polyacrylamide gel electrophoresis; MALDI–TOF, matrix-assisted laser desorption/ionization time-of-flight; MS, mass spectrometry; HBV, hepatitis B virus; HCV, hepatitis C virus; IEF, isoelectric focusing; SDS–PAGE, sodium dodecyl sulfate–polyacrylamide gel electrophoresis.
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