TABLE 1

Estimated 18F-LW223 Radiation Dose for Humans Is Within Acceptable Limits for Future Clinical Use

Estimated absorbed dose (×10−2 mGy/MBq)
Target organMale (n = 8)Female (n = 5)
Adrenals2.223.67
Brain0.590.56
Breasts0.720.86
Gallbladder wall2.012.46
Lower large intestine wall7.829.26
Small intestine1.111.30
Stomach wall0.941.15
Upper large intestine wall1.001.24
Heart wall2.031.89
Kidneys1.571.54
Liver1.301.95
Lung3.103.31
Muscle0.800.98
Ovaries1.66
Pancreas1.031.26
Red marrow0.820.98
Osteogenic cells1.201.52
Skin0.610.74
Spleen0.911.11
Testes0.77
Thymus0.901.07
Thyroid0.790.89
Urinary bladder wall1.161.48
Uterus1.29
Total body0.891.07
Effective dose (mSv/MBq)0.020.02