Binding Parameters from Test–Retest Study of 11C-LSN3172176
| 1TC VT (mL/cm3) (n = 6) | 1TC BPND (n = 6) | SRTM2 BPND (n = 6) | ||||||
| Region | Test | Retest | Minimum scan time (min) | Test | Retest | Minimum scan time (min) | Test | Retest |
| Ventral striatum | 48.5 (16%) | 48.9 (20%) | 50 | 8.87 (12%) | 8.69 (17%) | 50 | 8.60 (17%) | 8.00 (14%) |
| Putamen | 38.6 (22%) | 39.3 (22%) | 60 | 6.82 (20%) | 6.74 (18%) | 60 | 6.63 (23%) | 6.31 (16%) |
| Caudate | 30.2 (19%) | 30.4 (20%) | 60 | 5.13 (15%) | 4.98 (14%) | 70 | 4.97 (19%) | 4.64 (12%) |
| Amygdala | 28.8 (21%) | 28.8 (18%) | 40 | 4.80 (14%) | 4.67 (8%) | 50 | 4.62 (20%) | 4.3 (12%) |
| Temporal cortex | 27.4 (15%) | 27.9 (14%) | 60 | 4.56 (10%) | 4.52 (10%) | 70 | 4.41 (11%) | 4.25 (8%) |
| Occipital cortex | 26.7 (16%) | 27.3 (14%) | 60 | 4.42 (9%) | 4.41 (9%) | 70 | 4.28 (10%) | 4.17 (8%) |
| Parietal cortex | 25.5 (16%) | 26.1 (13%) | 60 | 4.18 (9%) | 4.16 (9%) | 60 | 4.04 (9%) | 3.94 (8%) |
| Frontal cortex | 24.4 (17%) | 24.7 (15%) | 60 | 3.96 (14%) | 3.88 (12%) | 70 | 3.83 (14%) | 3.67 (10%) |
| Hippocampus | 17.5 (18%) | 18.0 (15%) | 70 | 2.55 (16%) | 2.58 (16%) | 80 | 2.48 (21%) | 2.42 (17%) |
| Globus pallidus | 16.4 (24%) | 16.6 (24%) | 40 | 2.31 (25%) | 2.27 (24%) | 40 | 2.26 (28%) | 2.15 (23%) |
| Centrum semiovale | 9.0 (16%) | 9.4 (15%) | 30 | 0.82 (16%) | 0.85 (13%) | 40 | 0.77 (16%) | 0.78 (17%) |
| Thalamus | 8.7 (19%) | 9.0 (19%) | 30 | 0.76 (27%) | 0.76 (20%) | 30 | 0.75 (28%) | 0.75 (19%) |
| Cerebellum | 4.9 (12%) | 5.1 (14%) | 30 | |||||
Data are percentage coefficient of variation followed by intersubject variability in parentheses.