Binding Parameters from Baseline-Blocking Study of 11C-LSN3172176
| 1TC VT (mL/cm3) | 1TC BPND | |||
| Region | Baseline (n = 5) | Blocking (n = 4) | Baseline (n = 5) | Blocking (n = 4) |
| Ventral striatum | 44.6 (10%) | 34.0 (12%) | 7.82 (8%) | 5.68 (7%) |
| Putamen | 37.2 (9%) | 26.6 (11%) | 6.37 (7%) | 4.25 (11%) |
| Caudate | 29.7 (19%) | 21.2 (24%) | 4.85 (14%) | 3.14 (19%) |
| Amygdala | 27.4 (12%) | 18.9 (15%) | 4.44 (16%) | 2.71 (10%) |
| Temporal cortex | 24.7 (9%) | 16.5 (14%) | 3.89 (8%) | 2.25 (10%) |
| Occipital cortex | 23.8 (7%) | 14.9 (11%) | 3.71 (7%) | 1.94 (10%) |
| Parietal cortex | 23.1 (7%) | 14.9 (13%) | 3.59 (11%) | 1.94 (14%) |
| Frontal cortex | 22.5 (12%) | 14.6 (15%) | 3.45 (11%) | 1.88 (13%) |
| Hippocampus | 17.7 (11%) | 12.4 (13%) | 2.51 (15%) | 1.44 (13%) |
| Globus pallidus | 15.6 (9%) | 12.6 (17%) | 2.12 (24%) | 1.51 (35%) |
| Centrum semiovale | 8.7 (14%) | 6.8 (14%) | 0.72 (28%) | 0.34 (40%) |
| Thalamus | 9.4 (13%) | 7.3 (9%) | 0.86 (12%) | 0.43 (12%) |
| Cerebellum | 5.1 (11%) | 5.1 (10%) | ||
Data are percentage coefficient of variation followed by intersubject variability in parentheses.