TABLE 4

Comparison Between Control and PD Groups for Each Brain Hemisphere (and Interhemispheric) of Striatal 11C-DTBZ DVR and Mean QA

ControlPDControl vs. PD statistical significance
ParameterStriatumMean QAStriatumMean QAStriatumMean QA
Left3.24 ± 0.264.9 ± 0.9 (×10−3)1.88 ± 0.254.1 ± 0.7 (×10−3)t = 20.9; P < 10−6t = 3.9; P = 3 × 10−4
Right3.20 ± 0.265.1 ± 0.9 (×10−3)2.06 ± 0.333.2 ± 0.8 (×10−3)t = 14.9; P < 10−6t = 3.2; P = 0.002
Left vs. right statistical significancet = 1.8; P = 0.07t = −3.85; P = 0.002t = −5.3; P = 10−5t = −6.9; P < 10−6
  • Left hemisphere in PD group is hemisphere clinically most affected in PD patients; right hemisphere in PD group is hemisphere clinically least affected in PD patients.