Mechanism of Action with Antiresorptive and Anabolic Therapies
| Type of drug | Bone formation | Bone resorption |
| Antiresorptive therapy | Decrease | Decrease |
| Anabolic therapy (e.g., PTH analog) | Transient increase | Eventual increase |
| Anabolic therapy (e.g., sclerostin antibody) | Transient increase | Decrease |
PTH = parathyroid hormone.