TABLE 2

Baseline Physiologic Characteristics

NonsmokerSmoker
TraitHIV−HIV+HIV−HIV+pkw value
%HU950MLV*1.51 (2.5)1.53 (1.94)1.5 (1.17)1.31 (1.82)0.99
%HU910MLV*5.89 (11.36)3.55 (2.44)5.94 (4.45)2.46 (2.02)0.56
PASP (range)31.71 (25–39)35.25 (30–40)31.45 (23–44)33.81 (32–37)0.76
FEV13.62 (0.72)3.61 (0.53)3.37 (0.68)3.34 (0.81)0.66
FEV1, %predicted100.45 (16.05)94.83 (16.8)105.92 (25.96)107.11 (13.73)0.36
FVC4.52 (0.85)4.43 (0.70)4.24 (0.85)4.1 (0.99)0.62
FVC, % predicted102.38 (14.52)98.31 (14.70)108 (24.61)113.39 (13.32)0.14
  • * Measurement of Hounsfield units at MLV likely underestimates the amount of emphysema typically measured at total lung capacity (TLC).

  • Continuous variables are represented as mean (SD).

  • pkw = P value of the Kruskal–Wallis test; %HU950MLV = percentage of voxels with measured Hounsfield units < −950 at MLV; %HU910MLV = percentage of voxels with measured Hounsfield units < −910 at MLV; PASP = pulmonary arterial systolic pressure; FEV1 = forced expiratory volume in first second; FVC = forced vital capacity.