Baseline Physiologic Characteristics
Nonsmoker | Smoker | ||||
Trait | HIV− | HIV+ | HIV− | HIV+ | pkw value |
%HU950MLV* | 1.51 (2.5) | 1.53 (1.94) | 1.5 (1.17) | 1.31 (1.82) | 0.99 |
%HU910MLV* | 5.89 (11.36) | 3.55 (2.44) | 5.94 (4.45) | 2.46 (2.02) | 0.56 |
PASP (range) | 31.71 (25–39) | 35.25 (30–40) | 31.45 (23–44) | 33.81 (32–37) | 0.76 |
FEV1 | 3.62 (0.72) | 3.61 (0.53) | 3.37 (0.68) | 3.34 (0.81) | 0.66 |
FEV1, %predicted | 100.45 (16.05) | 94.83 (16.8) | 105.92 (25.96) | 107.11 (13.73) | 0.36 |
FVC | 4.52 (0.85) | 4.43 (0.70) | 4.24 (0.85) | 4.1 (0.99) | 0.62 |
FVC, % predicted | 102.38 (14.52) | 98.31 (14.70) | 108 (24.61) | 113.39 (13.32) | 0.14 |
↵* Measurement of Hounsfield units at MLV likely underestimates the amount of emphysema typically measured at total lung capacity (TLC).
Continuous variables are represented as mean (SD).
pkw = P value of the Kruskal–Wallis test; %HU950MLV = percentage of voxels with measured Hounsfield units < −950 at MLV; %HU910MLV = percentage of voxels with measured Hounsfield units < −910 at MLV; PASP = pulmonary arterial systolic pressure; FEV1 = forced expiratory volume in first second; FVC = forced vital capacity.