TABLE 1

Binding Affinity (K_i) and Selectivity Profile of OF-NB1 and MF-NB1

Compound	K_i GluN2B ± SD (nM)	K_i σ1 ± SD (nM)	σ1/GluN2B selectivity^*
OF-NB1	10.4 ± 4.7	410	39
MF-NB1	590 ± 36	2,700	4.6

↵* GluN2B selectivity was calculated as follows: (K_i σ1)/(K_i GluN2B).
Results are given as mean ± SD for n = 3.