TABLE 2

CTCAE Grading of New Clinical Toxicity per Patient During the 3 Months After Treatment

ToxicityCTCAE grade ICTCAE grade IICTCAE grade IIICTCAE grade IVCTCAE grade V
Abdominal pain16104
Nausea1592
Fatigue21102
Anorexia105
Dyspnea41
Fever711
Ascites12
Flulike symptoms21
Malaise41
Hepatic failure11*
Weight loss2
Chest pain12
Vomiting95
Dyspepsia11
Metal taste3
Contrast allergy12
Hematoma1
Diarrhea1
Constipation4
Upper gastrointestinal tract bleeding1
Limb edema2
Dizziness1
Chills2
Any clinical toxicity131971
Lowered albumin94
Elevated alanine aminotransferase2411
Elevated alkaline phosphatase4142
Elevated aspartate aminotransferase282
Elevated bilirubin212
Elevated γ-glutamyltransferase5155
Any laboratory toxicity72352
  • * Radioembolization-induced liver disease.

  • Highest CTCAE grades per clinical symptom or laboratory value are represented.