Study Group Characteristics and Odds Ratios (ORs) for Having Advanced Disease Compared with Reference
| Characteristic | Study group (n = 691) | Advanced disease on 68Ga-PSMA PET/CT | Univariate ORs of advanced disease | Multivariate ORs of advanced disease |
| Age (y) | ||||
| Median | 70.4 | |||
| Range | 45.2–87.2 | |||
| Time from biopsy to scan (mo) | ||||
| Median | 0.7 | |||
| Range | 0.1–5.1 | |||
| Prescan PSA (ng/mL) | ||||
| <10 | 200 (28.9%) | 37 (18.5%) | Reference = 1 | Reference = 1 |
| 10–20 | 194 (28.1%) | 58 (29.9%) | OR1 = 1.88 (1.17, 3.01) | OR1 = 1.45 (0.86, 2.47) |
| >20 | 297 (43.0%) | 149 (50.2%) | OR2 = 4.44 (2.90, 6.77) | OR2 = 4.32 (2.66, 7.12) |
| Unknown | 0 (0.0%) | |||
| ISUP grade in biopsies | ||||
| 1 | 41 (5.9%) | 1 (2.4%) | Reference = 1 | Reference = 1 |
| 2 | 102 (14.8%) | 11 (10.8%) | OR1 = 4.84 (0.89, 89.87) | OR1 = 3.75 (0.67, 70.51) |
| 3 | 89 (12.9%) | 33 (37.1%) | OR2 = 23.57 (4.76, 427.76) | OR2 = 19.67 (3.84, 361.15) |
| 4 | 262 (38.0%) | 81 (30.9%) | OR3 = 17.90 (3.79, 320.27) | OR3 = 25.55 (5.21, 462.70) |
| 5 | 196 (28.4%) | 117 (59.7%) | OR4 = 59.24 (12.47, 1061.62) | OR4 = 53.17 (10.79, 964.19) |
| Unknown | 1 (0.1%) | |||
| Clinical stage* | ||||
| cT1 | 123 (17.8%) | 13 (10.6%) | Reference = 1 | Reference = 1 |
| cT2 | 246 (35.6%) | 60 (24.4%) | OR1 = 2.73 (1.47, 5.40) | OR1 = 2.18 (1.13, 4.45) |
| cT3 | 314 (45.4%) | 165 (52.5%) | OR2 = 9.37 (5.23, 18.11) | OR2 = 7.13 (3.80, 14.29) |
| cT4 | 8 (1.2%) | 6 (75.0%) | OR3 = 25.38 (5.25, 186.23) | OR3 = 17.26 (2.82, 160.69) |
| Unknown | 0 (0.0%) |
↵* Digital rectal examination.
Qualitative data are numbers followed by percentages in parentheses; continuous data are OR followed by 95% CI in parentheses.