TABLE 1

Dose Estimates for 18F- and 68Ga-FAPI-74 According to OLINDA/EXM

Target organMean 18F-FAPI-74 ± SD (n = 10)68Ga-FAPI-74 (n = 1)
Adrenals1.15 ± 0.091.29
Brain0.78 ± 0.091.05
Breasts0.78 ± 0.071.04
Gallbladder wall1.17 ± 0.101.33
Lower large intestine wall1.23 ± 0.161.31
Small intestine1.16 ± 0.121.29
Stomach wall1.06 ± 0.101.24
Upper large intestine wall1.13 ± 0.111.27
Heart wall2.29 ± 0.283.40
Kidneys2.94 ± 0.793.51
Liver1.50 ± 0.361.33
Lungs0.96 ± 0.071.16
Muscle0.94 ± 0.101.14
Ovaries1.25 ± 0.161.33
Pancreas1.18 ± 0.101.32
Red marrow1.12 ± 0.111.11
Osteogenic cells1.53 ± 0.141.70
Skin0.73 ± 0.081.00
Spleen1.67 ± 0.441.19
Testes0.99 ± 0.131.16
Thymus1.02 ± 0.091.21
Thyroid0.91 ± 0.091.13
Urinary bladder wall7.58 ± 2.849.86
Uterus1.49 ± 0.251.46
Total body0.97 ± 0.091.22
Effective dose1.41 ± 0.221.61
  • Data are absorbed dose (mSv/100 MBq).