TABLE 2

Concordance of Management Recommendations by Expert Panel Based on Evaluation of Bone Lesions on BS Plus ceCT or 18F-FDG PET Plus ceCT

Recommendation18F-FDG PET plus ceCTBS plus ceCTConcordant recommendation
Treatment intent
 Curative7 (6.9)11 (10.8)5 (4.9)
 Noncurative83 (81.4)77 (75.5)76 (74.5)
 Unable to determine3 (2.9)5 (4.9)1 (1.1)
 Not evaluated*9 (8.8)9 (8.8)9 (8.8)
Systemic therapy
 None02 (2.0)0
 Antihormonal57 (55.9)53 (52.0)51 (50)
 Chemotherapy14 (13.7)10 (9.8)10 (9.8)
 Chemotherapy plus targeted therapy17 (16.7)16 (15.7)16 (15.7)
 Unable to determine5 (4.9)12 (11.8)3 (2.9)
 Not evaluated*9 (8.8)9 (8.8)9 (8.8)
CAD/bisphosphonate
 No15 (14.7)27 (26.5)14 (13.7)
 Yes77 (75.5)62 (60.8)62 (60.8)
 Unable to determine1 (1.0)4 (3.9)0
 Not evaluated*9 (8.8)9 (8.8)9 (8.8)
Radiotherapy
 None62 (60.8)56 (60.2)39 (38.2)
 Curative10 (9.8)6 (6.5)2 (2.0)
 Noncurative20 (19.6)25 (26.9)8 (7.8)
 Unable to determine1 (1.0)6 (6.5)1 (1.0)
 Not evaluated*9 (8.8)9 (8.8)9 (8.8)
Radiography/MRI
 No63 (61.8)65 (63.7)53 (52.0)
 Yes30 (29.4)28 (27.5)18 (17.6)
 Not evaluated*9 (8.8)9 (8.8)9 (8.8)
Other imaging
 No92 (90.2)66 (64.7)39 (38.2)
 Yes1 (1.0)27 (26.5)1 (1.0)
 Not evaluated*9 (8.8)9 (8.8)9 (8.8)
  • * For patients without bone lesions on any imaging modalities, it was assumed that management recommendations would be concordant between scenarios with 18F-FDG PET plus ceCT and BS plus ceCT and that there would be no requests for additional imaging to evaluate bone lesions, without evaluation of expert panel.

  • Additional 18F-FDG PET in case of available BS and vice versa.

  • CAD = calcium, vitamin D.

  • Data are numbers followed by percentages in parentheses. n = 102 patients.