Comparison of 18F-DCFPyl Uptake in Normal Tissues in Control and MSG Studies
| Average SULmean | Average SULmax | |||||||
| Tissue | Control (n = 10) | MSG (n = 10) | Decrease (%) (n = 10) | P* | Control (n = 10) | MSG (n = 10) | Decrease (%) (n = 10) | P* |
| Blood pool | 0.8 ± 0.1 | 0.7 ± 0.1 | 10.7 ± 12.5 | 0.021 | 1.1 ± 0.2 | 0.9 ± 0.2 | 11.4 ± 19.1 | 0.081 |
| Gluteus muscle | 0.2 ± 0.05 | 0.2 ± 0.04 | 7.9 ± 21.7 | 0.100 | 0.3 ± 0.1 | 0.3 ± 0.1 | 2.7 ± 27.9 | 0.364 |
| Liver | 4.5 ± 0.6 | 3.7 ± 0.6 | 15.7 ± 7.3 | <0.001 | 5.8 ± 0.7 | 4.9 ± 0.7 | 14.6 ± 5.7 | <0.001 |
| Spleen | 3.2 ± 0.9 | 2.1 ± 0.6 | 34.3 ± 11.1 | <0.001 | 3.6 ± 1.1 | 2.5 ± 0.6 | 28.3 ± 13.4 | 0.001 |
| Parotid glands | 9.1 ± 2.5 | 6.9 ± 2.9 | 26.1 ± 16.9 | 0.003 | 15.3 ± 3.9 | 11.6 ± 3.8 | 23.9 ± 14.0 | 0.001 |
| Submandibular glands | 8.9 ± 3.5 | 5.8 ± 2.9 | 34.7 ± 18.7 | 0.001 | 15.1 ± 6.2 | 9.9 ± 4.8 | 35.0 ± 11.2 | <0.001 |
| Lacrimal glands | 6.0 ± 1.3 | 3.4 ± 1.2 | 41.9 ± 18.9 | <0.001 | 9.9 ± 3.4 | 5.1 ± 1.9 | 48.5 ± 12.5 | <0.001 |
| Colon | 5.9 ± 1.2 | 3.3 ± 1.2 | 45.1 ± 13.8 | <0.001 | 7.5 ± 1.4 | 4.2 ± 1.3 | 43.8 ± 12.9 | <0.001 |
| Urinary bladder | 33.8 ± 9.9 | 27.9 ± 10.2 | 14.8 ± 30.2 | 0.054 | 73.0 ± 29.3 | 63.5 ± 33.8 | 14.4 ± 32.5 | 0.124 |
| Kidneys | 17.2 ± 4.6 | 12.1 ± 2.2 | 27.4 ± 12.1 | 0.001 | 37.5 ± 9.6 | 27.4 ± 8.0 | 23.5 ± 26.1 | 0.012 |
↵* Adjusted for multiple testing using Benjamini–Hochberg method.
Boldface values indicate statistical significance at α = 0.05 level.