TABLE 1

Methodology for Esophagogastrointestinal Transit Study

Parameter	Methodology
Esophageal transit	¹¹¹In-DTPA, 3.7 MBq, in 15 mL of water
	0.5-s frames × 60
	Transit quantification (percentage of counts 10 s after maximum counts)
Liquid-only gastric emptying	¹¹¹In-DTPA, 3.7 MBq, in 300 mL of water
	1-min frames × 60, in left anterior oblique view
	Transit quantification (half-time of emptying and fitted half-time)
Combined liquid/solid gastric emptying	¹¹¹In-DTPA, 3.7 MBq, in 120 mL of water and consensus standardized egg-white solid meal ingested over 10–15 min
	1.0-min anterior and posterior images immediately and 1, 2, 3, and 4 h after meal ingestion
	Transit quantification (liquid: percentage emptying at 1, 2, 3, and 4 h and emptying half-time; first-hour value used)
Solid gastric emptying	Protocol of Tougas et al. (19); 74 MBq of ^99mTc-sulfur colloid–labeled egg-white meal; geometric mean attenuation correction and percentage emptying at 0, 1, 2, 3, and 4 h
Small-intestinal transit index	1-min anterior and posterior images on ¹¹¹In photopeaks at 5 and 6 h; geometric mean attenuation correction; quantification at 6 h (percentage activity reaching region of ileocecal valve and beyond)
Large-intestinal transit	5-min anterior and posterior images on ¹¹¹In photopeaks acquired in morning at 24, 48, and 72 h; geometric mean attenuation correction
	Transit quantification (percentage activity present at 6 h that transits out of body at 24, 48, and 72 h; visual description of extent of transit at each time interval

Patients are instructed to fast overnight before examination and not to eat or drink anything further on day 1. Normal eating can resume on days 2, 3, and 4. Laxatives are prohibited on examination days until completed.