TABLE 1

Premedication Used to Reduce Brown Fat Uptake

Name of medicationRoute of administrationRecommended doseMaximum doseTime of administrationComments and precautions
Propranolol (6467).Oral1 mg/kg usually 20–40 mg40 mg60–90 min before 18F-FDG injectionRecommended for patients older than 10 y
Fentanyl (63,64,66)Intravenous1.0 μg/kg for patients less than 25 kg50 μg10 min before 18F-FDG injectionShould be injected under the supervision and monitoring of a physician or a trained nurse according to the institutional sedation policy
0.75 μg/kg for patients less than 25 kg
Diazepam (63,69)Oral0.080–0.096 mg/kg7.5 mg30–60 min before 18F-FDG injectionEspecially useful for anxious patients