TABLE 3

Cox Proportional Hazards Regression Analysis on Association of Multiple Variables and OS after ²²³Ra Treatment

	Univariate regression			Cox multiple regression
Variable	P	Hazard ratio	95% CI	P	Hazard ratio	95% CI
%ID (per 1 unit)	0.005	1.046	1.014–1.079
%ID/L(per 1 unit)	0.003	1.259	1.083–1.464	<0.001	1.381	1.162–1.643
SUV_mean (per 1 unit)	0.068	1.225	0.985–1.523
SUV_max (per 1 unit)	0.920	1.00	0.991–1.008
Age (per year)	0.159	1.033	0.987–1.080
Tumor load (per 1 category)	0.015	1.744	1.112–2.736
Prior treatment lines (1, 2, 3 or more)	0.007	1.488	1.116–1.984	<0.001	1.676	1.258–2.234
Prior chemotherapy (yes vs. no)	0.039	2.031	1.038–3.974
Log₁₀ prostate-specific antigen (per 1 unit)	0.476	1.175	0.754–1.829