Characteristics of scFv-Fc-CD44 After Radiolabeling With 64Cu ([64Cu]Cu-NOTA-scFv-Fc-CD44) or 89Zr ([89Zr]Zr-DFO-scFv-Fc-CD44)
| Parameter | n | [64Cu]Cu-NOTA-scFv-Fc-CD44 | [89Zr]Zr-DFO-scFv-Fc-CD44 |
| ITLC (% region of interest) | 3 | 100.00 ± 0.0 | 99.9 ± 0.0 |
| Specific activity | 3 | ||
| MBq/mg | 84.7 ± 11.0 | 80.0 ± 5.5 | |
| mCi/mg | 2.3 ± 0.3 | 2.2 ± 0.1 | |
| Labeling efficiency (%) | 3 | 59.6 ± 3.5 | 75.0 ± 7.1 |
| Immunoreactivity (%) | 64Cu, 2; 89Zr, 3 | 88.1 ± 3.7 | 87.9 ± 1.9 |
| Blocking efficiency (%) | 64Cu, 2; 89Zr, 3 | 99.8 ± 0.0 | 97.5 ± 0.5 |
| Internalization: specific half-life (min) | 64Cu, 2; 89Zr, 3 | 57.8 ± 34.9 | 56.4 ± 6.1 |
Data are mean ± SE.