TABLE 2

Clinical Characteristics of MAS Participants

Patient no.Age (y)SexScan typeMAS endocrinopathiesNeuropsychiatric disorderFibrous dysplasia locationsSkeletal burden score*
134FWhole body, brainHistory of precocious puberty, hyperthyroidismMajor depressive disorderCf, Ax, Ap61
220FWhole bodyNoneDepression, mild cognitive impairment, schizophrenia/schizoaffective disorder, anxietyCf7
355FWhole body, brainGrowth hormone excessNoneCf, Ax, Ap18
447FWhole body, brainHistory of precocious pubertyNoneCf, Ax3
533MWhole bodyGrowth hormone excess, hyperthyroidismNoneCf, Ax, Ap75
644FWhole bodyHistory of precocious puberty, hyperthyroidismNoneCf, Ax, Ap36
  • * Validated tool for quantifying fibrous dysplasia involvement (34).

  • Cf = craniofacial skeleton; Ax = axillary skeleton; Ap = appendicular skeleton.