Clinical Characteristics of MAS Participants
Patient no. | Age (y) | Sex | Scan type | MAS endocrinopathies | Neuropsychiatric disorder | Fibrous dysplasia locations | Skeletal burden score* |
1 | 34 | F | Whole body, brain | History of precocious puberty, hyperthyroidism | Major depressive disorder | Cf, Ax, Ap | 61 |
2 | 20 | F | Whole body | None | Depression, mild cognitive impairment, schizophrenia/schizoaffective disorder, anxiety | Cf | 7 |
3 | 55 | F | Whole body, brain | Growth hormone excess | None | Cf, Ax, Ap | 18 |
4 | 47 | F | Whole body, brain | History of precocious puberty | None | Cf, Ax | 3 |
5 | 33 | M | Whole body | Growth hormone excess, hyperthyroidism | None | Cf, Ax, Ap | 75 |
6 | 44 | F | Whole body | History of precocious puberty, hyperthyroidism | None | Cf, Ax, Ap | 36 |
↵* Validated tool for quantifying fibrous dysplasia involvement (34).
Cf = craniofacial skeleton; Ax = axillary skeleton; Ap = appendicular skeleton.