TABLE 4

OS According to Metabolic Parameters (Cox Models)

		Unadjusted models			Adjusted models*
Parameter	n	HR	95% CI	P	HR	95% CI	P
Median cervical tumor SUV_max
6.0; 14.8	34	Ref			Ref
15.0; 38.2	34	1.61	0.79–3.29	0.192	1.60	0.74–3.47	0.233
Median cervical tumor size
26; 57	34	Ref			Ref
58; 127	34	2.49	1.20–5.17	0.014	2.24	0.92–5.43	0.076
Median pelvic lymph node SUV_max
1.8; 7.5	31	Ref			Ref
8.11; 21.2	31	2.27	1.03–5.03	0.043	2.27	0.82–5.62	0.077^†
Median pelvic lymph node TLG
0.4; 12.5	32	Ref			Ref
13.0; 300.7	30	2.93	1.19–6.67	0.010	3.72	1.48–9.35	0.005^†
Threshold PALN SUV_max
1.5; 3.3	23	Ref			Ref
3.3; 24.3	28	4.67	1.57–13.87	0.005	4.80	1.44–16.05	0.011^†
Median PALN TLG
0.3; 2.2	27	Ref			Ref
2.4; 115.0	25	3.00	1.22–7.39	0.017	3.11	1.06–9.19	0.039^†

↵* Adjustment on quartiles of age, FIGO stage, and histologic subtype.
↵† Cox-estimated survival curves (terciles) compatible with a dose effect.
Ref = n = numbers by modality; HR = hazard ratio; and 95% CI = 95% confidence interval.