Ex Vivo and In Vitro Stabilities of 11C-NR2B-SMe in Rat Tissues
| Radioactive sample | Ex vivo stability (%) | In vitro stability (%) |
| Whole blood | 89.8 | |
| Plasma | 71.6 | 90.4 |
| Brain | 99.2 | 97.0 |
| Myocardium | 90.0 |
Measurements were made at 30 min after intravenous injection of radioligand ex vivo and at 30 min after incubation of radioligand at 37°C in vitro. Stabilities are represented by ratios of percentage of parent radioligand in tissue to fractional radioligand purity at start of study. Formulated radioligand was initially 98.4% pure and found to be 99.2% intact 3 h later at end of other measurements.