TABLE 2
Monoexponential Function Fitting Parameters and Time-Integrated Activity Coefficients (Residence Times) for 68Ga-FAPI-46 in Various Organs
| Organ | A (%IA) | λ (h−1) | TIAC (h) |
| Liver | 3.49 (2.26) | 0.88 (0.12) | 0.0378 (0.0198) |
| Kidney | 2.07 (0.65) | 1.08 (0.26) | 0.0195 (0.0062) |
| Bladder | 6.82 (2.32) | 1.47 (0.91) | 0.0595 (0.0319) |
| Heart | 1.69 (0.30) | 0.94 (0.06) | 0.0182 (0.0035) |
| Spleen | 0.71 (0.62) | 0.96 (0.12) | 0.0074 (0.0066) |
| Marrow | 2.61 (0.63) | 2.05 (2.97) | 0.0250 (0.0114) |
| Uterus (n = 2) | 0.13 (0.004) | 0.50 (0.07) | 0.0027 (0.0005) |
A = activity, expressed as %IA = percentage injected activity;
; λ = rate constant; TIAC = time-integrated activity coefficient.Data are mean followed by SD in parentheses for 6 patients. Representative percentage injected activity curves with monoexponential curve fits overlaid are available in Supplemental Figure 1. Per-patient coefficients and TIACs are available in Supplemental Table 2.
