TABLE 1

Patient Characteristics

Restaging
CharacteristicInitial staging: treatment-naïveAfter ADTAfter surgery, PSA < 0.2After RT, PSA < nadir + 2Other primary treatmentAdvanced diseaseFull cohort
Number of patients30 (15%)16(8%)13(7%)22(11%)13(6%)103(52%)197
Mean age (y)69.70 ± 7.02 (51–85)64.38 ± 9.53 (49–82)68.85 ± 8.73 (47–76)69.82 ± 8.06 (56–86)63.85 ± 8.86 (49–77)69.72 ± 8.61 (46–95)68.52 ± 8.64 (46–95)
Mean PSA at time of PET ( ng/mL)19.43 ± 27.58 (2.4–135.50)62.48 ± 100.36 (0.17–322)0.13 ± 0.05 (0.04–0.2)1.79 ± 1.31 (0.3–5.6)11.53 ± 19.65 (1.10–74.30)40.66 ± 188.04 (0.02–1,789)30.03 ± 139.95 (0.02 –1,789)
PSA (ng/mL) at time of PSMA PET*t2 to ≤5: 60 to ≤0.2: 10 to ≤0.2: 130 to ≤0.2: 00 to ≤0.2: 00 to ≤0.2: 100 to ≤0.2: 24
5 to ≤10: 110.2 to ≤0.5: 20.2 to ≤0.5: 00.2 to ≤0.5: 30.2 to ≤0.5: 00.2 to ≤0.5: 160.2 to ≤0.5: 21
10 to ≤20: 50.5 to ≤2: 20.5 to ≤2: 00.5 to ≤2: 100.5 to ≤2: 10.5 to ≤2: 250.5 to ≤2: 38
>20: 8>2: 11>2: 0>2: 9>2: 12>2: 52>2: 114
Currently under ADT016 (100%)4 (13%)5 (20%)037 (43%)59 (30%)
Gleason score≤: 19≤7: 4≤7: 8≤7: 12≤7: 7≤7: 41≤7: 91
≥8: 11≥8: 10≥8: 4≥8: 6≥8: 3≥8: 45≥8: 79
Unknown: 0Unknown: 2Unknown: 1Unknown: 4Unknown: 3Unknown: 17Unknown: 27
  • * Serum PSA ranges used for treatment-naïve group are different from other groups.

  • ADT = androgen deprivation therapy; known M1 = known metastatic disease.

  • Qualitative data are expressed as number followed by percentage in parentheses; continuous data are expressed as mean ± SD followed by range in parentheses.