Clinical Scenarios for the Use of PET MPI in Asymptomatic Patients (Without Symptoms or Ischemic Equivalent)
| Scenario no. | Description | Appropriateness | Score |
| Asymptomatic patients by pretest CAD risk | |||
| 16 | Asymptomatic patients with a low pretest global CAD risk (<7.5%) | Rarely Appropriate | 1 |
| 17 | Asymptomatic patients with an intermediate pretest global CAD risk (7.5%–20%), who have an interpretable resting ECG and are able to exercise | Rarely Appropriate | 2 |
| 18 | Asymptomatic patients with an intermediate pretest global CAD risk (7.5%–20%), who have an uninterpretable resting ECG or are unable to exercise | May be Appropriate | 5 |
| 19 | Asymptomatic patients with a high pretest probability of CAD (>20%) | May be Appropriate | 5 |
| 20 | Asymptomatic patient with an intermediate pretest CAD risk (7.5%–20%), who have a calcium score of 400–1,000 | May be Appropriate | 6 |
| 21 | Asymptomatic patients with a high pretest CAD risk (>20%), who have a calcium score of 400–1,000 | Appropriate | 8 |
| 22 | Asymptomatic patients who have a calcium score of >1,000 | Appropriate | 8 |
| 23 | Asymptomatic patients with peripheral vascular disease | May be Appropriate | 5 |
| 24 | Asymptomatic patients with a family history of premature CAD | Rarely Appropriate | 3 |
| 25 | Asymptomatic patients with familial hyperlipidemia | May be Appropriate | 5 |
| Asymptomatic patients with equivocal or abnormal prior test results | |||
| 26 | Asymptomatic patients with equivocal or abnormal prior test results from CCTA or ICA | Appropriate | 8 |
| 27 | Asymptomatic patients with recent (<90 d) equivocal or abnormal prior test results from stress testing (imaging or nonimaging) | May be Appropriate | 6 |
| 28 | Asymptomatic patients with regional or global LV systolic dysfunction | Appropriate | 8 |
| 29 | Asymptomatic patients with new LBBB | Appropriate | 8 |
| 30 | Asymptomatic patients with AF | May be Appropriate | 5 |
| 31 | Asymptomatic patients with abnormal resting ECG results that show abnormal or pathologic Q waves | May be Appropriate | 6 |
| 32 | Asymptomatic patients with abnormal resting ECG results that show ST-T segment abnormalities | May be Appropriate | 5 |
| 33 | Asymptomatic patients with known stable CAD without prior revascularization | May be Appropriate | 6 |
| Asymptomatic patients with a history of revascularization (PCI or CABG) | |||
| 34 | Asymptomatic patients with a history of PCI of <2 y | Rarely Appropriate | 2 |
| 35 | Asymptomatic patients with a history of PCI of >2 y | May be Appropriate | 6 |
| 36 | Asymptomatic patients with a prior CABG of <5 y | Rarely Appropriate | 2 |
| 37 | Asymptomatic patients with a prior CABG of >5 y | May be Appropriate | 6 |
| Asymptomatic patients with prior heart transplantation | |||
| 38 | Evaluation for CAV in asymptomatic patients with prior heart transplantation | Appropriate | 8 |
| Asymptomatic patients being considered for solid organ transplantation (kidney, lung, liver) | |||
| 39 | Evaluation for CAD in patients being considered for solid organ transplantation (e.g., kidney, lung, liver) | Appropriate | 8 |
| Asymptomatic patients undergoing cancer treatment | |||
| 40 | Asymptomatic patients during or after chemotherapy or radiation therapy for cancer who have a reduced LVEF | May be Appropriate | 5 |
| 41 | Asymptomatic patients during or after chemotherapy or radiation therapy for cancer | Rarely Appropriate | 1 |
| Asymptomatic patients with a history of coronary vasculitis or high-risk coronary anomalies | |||
| 42 | Asymptomatic patients with a history of coronary vasculitis and evidence of structurally abnormal coronary arteries (e.g., aneurysms) | Appropriate | 7 |
| 43 | Asymptomatic patients with a history of high-risk coronary anomalies | May be Appropriate | 5 |