Studies Comparing Methods of Lung Quantification
| Author | Year | Study type | No. of patients | No. of pneumonectomies or lobectomies | Comparison to postoperative tests | Scan methods compared | Optimal method |
| Piai (11) | 2004 | Prospective | 26 | 13/13 | Yes | PS vs. SPECT | PS = SPECT |
| Mineo (10) | 2006 | Prospective | 39 | 11/28 | Yes | PS vs. SPECT | PS = SPECT |
| Yoshimoto (13) | 2009 | Prospective | 37 | 0/37 | Yes | SC vs. CT and SPECT/CT | CT and SPECT/CT |
| Ohno (14) | 2011 | Prospective | 229 | 14/215* | Yes | CT vs. MRI, PS, SPECT, and coregistered SPECT/CT | CT, MRI, and SPECT/CT |
| Toney (15) | 2014 | Retrospective | 17 | NA | No | PS vs. SPECT/CT | NA |
| Kovacević-Kuśmierek (17) | 2015 | Not mentioned | 70 | 47/23 | Yes | SC vs. PS, SPECT, and SPECT/CT | PS |
| Le Roux (21) | 2016 | Retrospective | 22† | 1/13† | No | PS vs. Q PET/CT | NA |
| Nagamatsu (16) | 2016 | Prospective | 18 | 0/18 | Yes | SC vs. coregistered SPECT/CT | SC = coregistered SPECT/CT |
| Suh (18) | 2017 | Prospective | 55 | 2/32* (21, no surgery) | Yes (9 patients) | PS (AP and PO) vs. SPECT/CT | SPECT/CT |
| Genseke (19) | 2018 | Retrospective | 39 | Not mentioned (32, no surgery) | No | PS vs. SPECT/CT | NA |
| Current study | 2019 | Prospective | 75 | 60 | Yes (60 patients) | SC vs. PS and SPECT/CT | SC = PS = SPECT/CT |
↵* Including segmentectomy or bilobectomy in lobectomy group.
↵† Only 16 patients underwent both quantitative PET/CT and planar scanning (13 lobectomy, 4 segmentectomy, 1 pneumonectomy, 4 no operation).
SPECT = perfusion scintigraphy with SPECT quantitation; CT = quantitative CT; SPECT/CT = perfusion scintigraphy with SPECT/CT quantitation; MRI = perfusion MRI; coregistered SPECT/CT = CT and SPECT performed separately and coregistered with software; NA = not applicable (no gold standard test used); AP = anterior-posterior; PO = posterior-oblique.