Demographics and Baseline Characteristics (Safety Population)
| Characteristic | Dose-ranging study (n = 12) | Phase III study (n = 63) |
| Age (y) | ||
| Mean | 62.0 (12.7) | 54.4 (15.7) |
| Median | 59.5 (44.0, 83.0) | 54.0 (25.0, 82.0) |
| Height (cm) | ||
| Mean | 172.1 (9.9) | 171.9 (11.43) |
| Median | 171.4 (157.4, 193.0) | 172.7 (147.3, 199.9) |
| Weight (kg) | ||
| Mean | 72.4 (19.8) | 84.3 (21.2) |
| Median | 69.8 (45.3, 113.4) | 80.7 (51.7, 148.3) |
| Sex | ||
| Male | 5 (41.7) | 28 (44.4) |
| Female | 7 (58.3) | 35 (55.6) |
| Race | ||
| American Indian or Alaska Native | 0 (0) | 0 (0) |
| Asian | 0 (0) | 2 (3.2) |
| Black or African American | 0 (0) | 6 (9.5) |
| Native Hawaiian or other Pacific Islander | 0 (0) | 0 (0) |
| White | 12 (100.0) | 54 (85.7) |
| Other | 0 (0) | 1 (1.6) |
| Ethnicity | ||
| Hispanic or Latino | 0 (0) | 11 (17.5) |
| Not Hispanic or Latino | 12 (100.0) | 52 (82.5) |
| Unknown | 0 (0) | 0 (0) |
| Not reported | 0 (0) | 0 (0) |
Qualitative data are numbers followed by percentages in parentheses; continuous data are mean followed by SD and median followed by range in parentheses.