Uni- and Multivariate Analysis for Local Control in Training Set
| Univariate | Multivariate | |||||
| Characteristic | HR | 95% CI | P | HR | 95% CI | P |
| Age (<72 vs. ≥72 y) | — | — | 0.975 | |||
| Tumor volume (>132 vs. ≤132 cm3) | — | — | 0.059 | |||
| TNM (T2 vs. T1) | 6 | 0.1–405 | 0.078 | |||
| Sex (male vs. female) | 3 | 0.3–29 | 0.251 | |||
| Histopathologic type (others vs. ADK) | 3 | 0.4–21 | 0.297 | |||
| WHO performance status (≤1 vs. 2) | — | — | 0.420 | |||
| Localization (peripheral vs. central) | — | — | 0.793 | |||
| BED10 (>151.2 vs. ≤151.2 Gy) | — | — | 0.016 | |||
| Radiomic signature | ||||||
| PET signature (IC2 and strength) | — | — | <0.001 | 30.75 | 2.56–369.11 | 0.007 |
| PET/CT signature (PET IC2 and CT flatness) | — | — | <0.001 | 37.5 | 3.13–448.61 | 0.004 |
ADK = adenocarcinoma; WHO = World Health Organization; BED10 = biologically equivalent dose.