TABLE 1

Parameters in Selecting Optimal Image Metrics for Response to Therapy

SUV metricRCF scoreUncertain fractionQRAS
ΔSUVmax0.730.730.450.45
ΔSUV250.280.720.310.12
ΔSUV25 (single slice)0.330.740.340.15
ΔSUVP40.590.770.480.37
ΔSUVP140.470.740.340.22
ΔSUVP330.450.690.410.27
  • F score is derived from performance evaluation of response to therapy. “Uncertain fraction” is fraction of data points within limits of agreement for a given image metric QRAS=RC · (uncertain fraction)/(F score). Lower QRAS value is favorable.