Parameters in Selecting Optimal Image Metrics for Response to Therapy
SUV metric | RC | F score | Uncertain fraction | QRAS |
ΔSUVmax | 0.73 | 0.73 | 0.45 | 0.45 |
ΔSUV25 | 0.28 | 0.72 | 0.31 | 0.12 |
ΔSUV25 (single slice) | 0.33 | 0.74 | 0.34 | 0.15 |
ΔSUVP4 | 0.59 | 0.77 | 0.48 | 0.37 |
ΔSUVP14 | 0.47 | 0.74 | 0.34 | 0.22 |
ΔSUVP33 | 0.45 | 0.69 | 0.41 | 0.27 |
F score is derived from performance evaluation of response to therapy. “Uncertain fraction” is fraction of data points within limits of agreement for a given image metric QRAS=RC · (uncertain fraction)/(F score). Lower QRAS value is favorable.