TABLE 1

Differences in Lesion Quantification Between DDG-Retro and the 3 Other Methods of Gating and Reconstruction

Difference (DDG-retro – other)
Parameter/DDG-retro with…Lesions (n)Mean25th, 75th percentilesP
SUVmax/RPM-gated870.66 ± 0.1 g/mL0.00, 0.87 g/mL<0.0005
SUVmax/ungated-matched1071.3 ± 0.2 g/mL0.06, 2.0 g/mL<0.0005
SUVmax/ungated-full1071.6 ± 0.2 g/mL0.38, 2.0 g/mL<0.0005
SUVmean/RPM-gated540.44 ± 0.1 g/mL−0.01, 0.60 g/mL0.003
SUVmean/ungated-matched640.97 ± 0.2 g/mL0.01, 1.60 g/mL<0.0005
SUVmean/ungated-full641.2 ± 0.2 g/mL0.36, 1.59 g/mL<0.0005
Lesion volume/RPM-gated54−0.30 ± 0.1 cm3−0.52, 0.03 cm30.009
Lesion volume/ungated-matched64−0.70 ± 0.2 cm3−0.98, −0.01 cm30.005
Lesion volume/ungated-full64−0.83 ± 0.2 cm3−1.05, −0.03 cm30.001
  • Data are mean differences (with SE on mean difference) and first and third quartiles, along with results from post hoc testing of transformed data. P values are uncorrected for multiple comparisons. Critical P value for statistical significance was 0.017 (lowered from 0.05 to allow for multiple comparisons).