TABLE 1

Clinical Data, Minimum SBRs, Minimum z Scores, and Antemortem and Postmortem Diagnoses for the 6 Patients Who Underwent 123I-FP-CIT SPECT and Then Neuropathologic Examination

SBR
DQMIMManual
Patient no.Age at scan (y)Time between last scan and death (y)StriatumCaudateStriatumCaudateStriatumCaudateDAT visual interpretationClinical diagnosis before deathUPDRSMMSECDR sum of boxes
1752.230.09 (−4.72)0.08 (−4.47)0.27 (−3.70)0.3 (−4.00).171.17AbnormalADem7N/A13
2552.062.56 (1.46)2.74 (1.18)2.77 (0.70)2.7 (0.10)2.073.08NormalADem + pDLB5153.5
3632.852.09 (0.47)2.10 (−0.10)1.98 (−0.70)2.05 (−1.00)1.792.83NormalADem069
4592.931.87 (−0.37)2.21 (−0.05)2.14 (−0.40)2.37 (−0.30)2.213.32NormalADem0146
5744.651.80 (0.09)2.07 (0.20)1.9 (−0.70)1.89 (−1.00)1.923.02NormalADem (lpvPPA)0202
6771.051.17 (−1.86)1.64 (−0.71)1.99 (−0.50)2.19 (−0.50)1.182.45AbnormalpDLB11216
  • DQ = DaTQUANT; DAT = 123I-FP-CIT SPECT; UPDRS = Unified Parkinson Disease Rating Scale; MMSE = Mini-Mental State Examination; CDR = Clinical Dementia Rating Staging Instrument; lpvPPA = logopenic variant primary progressive aphasia.

  • Data in parentheses are z scores.