TABLE 1

Clinical Characteristics of Study Sample

CharacteristicValue
Number of patients (n)56
Mean age (y)67.0 (range, 48–78; SD, ±7.9)
Prior treatment (n)*
 Radical prostatectomy10 (13%)
 Prostate bed radiation9 (11%)
 Metastasis-directed radiation4 (5%)
 Both radical prostatectomy and radiation therapy14 (18%)
 Androgen deprivation therapy or chemotherapy28 (35%)
 Other, unknown9 (11%)
 Currently undergoing androgen deprivation therapy or chemotherapy6 (8%)
Median PSA level (ng/mL)13.7 (range, 0.05–132.5)
PET/MR (n)40 (71%)
PET/CT (n)16 (29%)
Gleason score at diagnosis (n)
 3 + 35 (9%)
 3 + 48 (14%)
 4 + 38 (14%)
 4 + 412 (21%)
 4 + 513 (23%)
 5 + 45 (9%)
 5 + 52 (4%)
 Not applicable3 (5%)
PSMA PET findings (n)
 Bone lesions
  1 lesion22 (39%)
  2–4 lesions (oligometastatic)18 (32%)
  5+ lesions16 (29%)
  True-positive bone disease43 (77%)
  False-positive bone disease13 (23%)
 Lymph nodes
  None26 (46%)
  Pelvic only13 (23%)
  Nonregional only6 (11%)
  Pelvic and nonregional11 (20%)
 Other sites of metastatic disease0 (0%)
  • * Prior treatment percentage applies only to patients with biochemical recurrence.

  • PSA = prostate-specific antigen.