TABLE 2

Biodistribution Data of [18F]FGlc-FAPI in HT1080hFAP Xenografts for 30, 60, and 90 Minutes After Injection and of [18F]FGlc-FAPI Coinjected with Competitor 11 (30 nmol/mouse, Blocking) for 60 Minutes After Injection

Tissue30 min60 min90 min60-min blocking
Blood2.3 ± 0.91.1 ± 0.60.7 ± 0.20.2 ± 0.1
Lung1.5 ± 0.20.8 ± 0.30.5 ± 0.20.3 ± 0.1
Liver4.0 ± 1.42.2 ± 0.11.7 ± 0.22.9 ± 1.2
Kidney1.7 ± 0.11.5 ± 0.31.0 ± 0.21.4 ± 0.3
Heart1.3 ± 0.50.7 ± 0.50.4 ± 0.20.1 ± 0.1
Spleen1.0 ± 0.50.5 ± 0.10.3 ± 0.10.4 ± 0.3
Brain0.13 ± 0.020.05 ± 0.020.07 ± 0.030.02 ± 0.01
Muscle1.5 ± 0.31.2 ± 0.50.9 ± 0.20.2 ± 0.1
Femur3.2 ± 0.53.4 ± 0.62.6 ± 0.50.6 ± 0.8
HT1080hFAP Tumor1.6 ± 0.42.0 ± 0.51.6 ± 0.20.9 ± 0.2
Intestine6.1 ± 4.46.4 ± 6.05.2 ± 6.18.0 ± 9.9
  • Data are mean ± SD (n = 2).