TABLE 1

PSA Response After Each Cycle of Therapy for 3 Groups

Group AGroup BGroup C
PSA responseFirstSecondThirdAll*FirstSecondThirdAll*FirstSecondThirdAll*
PR0/10 (0.0%)2/9 (22.2%)1/4 (25.0%)1/10 (10.0%)4/10 (40.0%)5/9 (55.5%)2/5 (40.0%)4/10 (40.0%)2/8 (25.0%)5/8 (62.5%)4/5 (80.0%)5/8 (62.5%)
Stable disease4/10 (40.0%)0/9 (0.0%)0/4 (0.0%)0/10 (0.0%)4/10 (40.0%)1/9 (11.1%)2/5 (40.0%)3/10 (30.0%)3/8 (37.5%)1/8 (12.5%)0/5 (0.0%)1/8 (12.5%)
PD6/10 (60.0%)7/9 (77.7%)3/4 (75.0%)9/10 (90.0%)2/10 (20.0%)3/9 (33.3%)1/5 (20.0%)3/10 (30.0%)3/8 (37.5%)2/8 (25.0%)1/5 (20.0%)2/8 (25.0%)
  • * PSA response before and 8 wk after last cycle of treatment in all enrolled patients who had received at least 1 cycle of therapy.