Quantitative Assessment of Biodistribution for Different Uptake Times
SUVmean | SUVmean ratio | |||||||||||
Organ | Time 1 | Time 2 | Time 3 | Time 4 | P1 | P2 | Time 1 | Time 2 | Time 3 | Time 4 | P1 | P2 |
Background | 0.57 ± 0.07 | 0.54 ± 0.09 | 0.53 ± 0.06 | 0.53 ± 0.09 | 0.017* | 0.006* | — | — | — | — | — | — |
Blood pool | 2.01 ± 0.45 | 1.90 ± 0.37 | 1.81 ± 0.40 | 1.63 ± 0.32 | <0.001 | <0.001 | 3.54 ± 0.72 | 3.56 ± 0.54 | 3.48 ± 0.79 | 3.09 ± 0.48 | 0.001† | 0.015† |
Lung | 0.68 ± 0.16 | 0.64 ± 0.15 | 0.64 ± 0.14 | 0.57 ± 0.11 | 0.020* | 0.005* | 1.20 ± 0.29 | 1.21 ± 0.24 | 1.22 ± 0.28 | 1.10 ± 0.28 | 0.091 | 0.153 |
Kidney | 26.81 ± 6.76 | 29.08 ± 7.37 | 29.21 ± 7.39 | 30.13 ± 9.01 | 0.093 | 0.008 | 48.09 ± 14.63 | 55.80 ± 17.17 | 55.98 ± 16.53 | 58.95 ± 22.37 | 0.010 | 0.001 |
Bladder | 2.25 ± 1.28 | 2.84 ± 2.29 | 2.80 ± 1.42 | 4.22 ± 2.71 | <0.001 | <0.001 | 3.94 ± 2.16 | 5.48 ± 5.22 | 5.38 ± 2.79 | 8.22 ± 5.71 | <0.001 | <0.001 |
Bone | 1.06 ± 0.27 | 1.12 ± 0.27 | 1.13 ± 0.28 | 1.20 ± 0.43 | 0.322 | 0.052 | 1.90 ± 0.51 | 2.12 ± 0.55 | 2.17 ± 0.59 | 2.34 ± 0.10 | 0.043 | 0.004 |
Parotid | 15.21 ± 3.66 | 14.50 ± 4.72 | 15.05 ± 4.12 | 16.94 ± 4.52 | 0.048 | 0.108 | 27.10 ± 7.41 | 27.65 ± 10.19 | 28.94 ± 8.23 | 32.87 ± 10.07 | 0.012 | 0.003 |
SMG+ | 16.31 ± 3.16 | 16.28 ± 3.70 | 16.75 ± 4.86 | 18.71 ± 4.32 | 0.048 | 0.031 | 29.16 ± 7.28 | 30.96 ± 8.23 | 32.32 ± 9.93 | 36.20 ± 9.71 | 0.006 | <0.001 |
Liver | 8.50 ± 2.30 | 7.94 ± 2.28 | 8.29 ± 2.75 | 6.60 ± 2.18 | 0.007 | 0.005 | 15.13 ± 4.38 | 15.09 ± 4.74 | 15.92 ± 5.38 | 12.87 ± 4.86 | 0.090 | 0.204 |
Spleen | 9.67 ± 3.77 | 8.70 ± 3.10 | 9.47 ± 3.56 | 8.84 ± 3.12 | 0.476 | 0.313 | 17.30 ± 7.35 | 16.38 ± 5.78 | 18.21 ± 7.27 | 16.99 ± 6.26 | 0.525 | 0.176 |
Duodenum | 7.20 ± 2.46 | 6.47 ± 2.27 | 7.37 ± 2.92 | 7.31 ± 3.39 | 0.293 | 0.498 | 12.86 ± 4.59 | 12.28 ± 4.50 | 14.20 ± 5.89 | 13.91 ± 6.03 | 0.384 | 0.167 |
Pancreas | 2.403 ± 0.85 | 2.09 ± 0.53 | 2.13 ± 0.75 | 2.07 ± 0.57 | 0.094 | 0.014 | 4.31 ± 1.68 | 3.99 ± 1.21 | 4.09 ± 1.58 | 3.99 ± 1.46 | 0.742 | 0.148 |