Patient Characteristics
Patient no. | PSA (ng/mL) | Location of metastases | Previous pharmacotherapy | Previous radiotherapy | Previous radioactive drugs |
1 | 227 | LN, bone, liver, adrenal | Abi, Doce, Enza | RTx, bone | 177Lu (27.9 GBq) |
2 | 239 | Bone, LN, lung, skin | Keto, Estra, Doce, Abi, Trial, Enza | RTx, local and bone | 90Y (7.4 GBq) |
3 | 697 | LN, bone, adrenal | Abi, Doce, Trial, Cabazi | RTx, pelvic and bone | None |
4 | 111 | LN, bone | Abi, Enza, Doce | RTx, pelvic and bone | 177Lu (16 GBq) |
5 | 481 | Liver | Abi, Enza, Doce, Cabazi | RTx, local and pelvic | None |
6 | 759 | LN, bone | Abi, Enza, Doce, Cabazi | RTx, local, pelvic, and bone | 177Lu (44.4 GBq) |
7 | 1,658 | LN, bone | Abi, Doce, Cabazi, Estra, Enza | RTx, local and pelvic | None |
PSA = prostate-specific antigene; LN = lymph node; Abi = abiraterone; Doce = docetaxel; Enza = enzalutamide; RTx = radiotherapy; Keto = ketoconazole; Estra = estramustine; Trial = Phase-1 trial of BAY2010112 (NCT01723475); Cabazi = cabazitaxel.