TABLE 1

Overview of Several Molecular PSMA-Targeted Agents and Radioisotopes

RadioisotopePSMA ligandDescription
123IMIP-1072 and MIP-1095First agents for SPECT imaging
99mTcMIP-1404 and MIP-1405
18FDCFBCFirst agents for PET imaging
68GaPSMA-11
68Ga, 177Lu, 255AcPSMA-617Theranostic ligands
68Ga, 177Lu, 111InPSMA imaging and therapy (better known as PSMA I&T)
18F18F-DCFPyLSecond generation of tracers labeled with 18F
18F18F-PSMA-1007