TABLE 1

Stratification of Patients into Different Groups Based on Administered Activity and Acquisition Time

Group	Dose		Time			Mean BW (kg)	PSA (ng/mL)		Tumor locations (n)
Group	Subgroup	MBq	Subgroup	Min	n	Mean BW (kg)	Mean	Range	Local/prostate	LN	Bone	Visceral	Total
1	Dose 1	222–296	Time 1	50–70	20	69.1	16.7	2.6–95.3	14	23	4	1	42
2	Dose 1	222–296	Time 2	71–90	20	72.0	12.2	1.9–64.9	16	9	13	0	38
3	Dose 1	222–296	Time 3	91–110	20	72.0	12.0	0.9–81.6	12	17	7	0	36
4	Dose 1	222–296	Time 4	≥111	5	69.8	4.1	0.2–16.6	3	2	5	0	10
5	Dose 2	297–370	Time 1	50–70	20	83.0	12.2	2.3–39.5	12	10	14	0	36
6	Dose 2	297–370	Time 2	71–90	20	83.2	11.2	2.2–38.0	14	15	6	0	35
7	Dose 2	297–370	Time 3	91–110	20	82.2	12.1	2.3–41.4	13	17	13	0	43
8	Dose 2	297–370	Time 4	≥111	14	80.5	9.9	0.2–44.1	10	10	1	0	21
9	Dose 3	371–444	Time 1	50–70	20	100.4	12.3	2.0–60.0	13	20	11	1	45
10	Dose 3	371–444	Time 2	71–90	20	98.5	12.7	2.0–77.5	13	25	5	0	43
11	Dose 3	371–444	Time 3	91–110	16	99.3	9.0	0.2–62.7	10	8	2	0	20
12	Dose 3	371–444	Time 4	≥111	7	102.3	2.7	0.4–521	3	0	5	0	8
Total					202	84.1	11.6^*	0.1–95.3	133	156	86	2	377

↵* Mean PSA value from all patients.
BW = body weight; local = local recurrence; LN = lymph node.