Main Advantages and Disadvantages of Automated Synthesis Module vs. Kit
| 68Ga-PSMA-11 preparation | Synthesis module | Kit |
| Yield (%) corrected for decay | >80 | 99.9* |
| Time of synthesis (min) | 20 | 10 |
| 68Ga/68Ge eluate and product purification | Need to elute and purify product | No need to elute and purify product |
| Preparation of reagents before synthesis | Need to prepare cassette and reagents | All necessary materials are provided with kit |
| Installation and maintenance issues | Need to install and maintain module | No need to install and maintain module |
| Operational complexity | Need to train staff | Need to train staff, but less operational complexity |
| Radiochemical purity (%) | >98 | >98 |
| 68Ge content (%) | 0.00001 | 0.0001 |
| Ethanol content | Complied with European Pharmacopoeia specifications | Not present |
| Sterility and pyrogen content | Complied with European Pharmacopoeia specifications | Complied with European Pharmacopoeia specifications |
↵* All 68Ga activity from generator available as radiopharmaceutical.