Qualitative Analyses of Image Quality
| Parameter | Group | Dose 1 | Dose 2 | Dose 3 | P | Time 1 | Time 2 | Time 3 | Time 4 | P |
| Overall subjective | 1 | 37 (56.9%) | 27 (36.5%) | 11 (17.5%) | <0.001(F) | 30 (50.0%) | 17 (28.3%) | 19 (33.9%) | 9 (34.6%) | 0.069 (F) |
| 2 | 28 (43.1%) | 39 (52.7%) | 45 (71.4%) | <0.001 | 27 (45.0%) | 39 (65.0%) | 34 (60.7%) | 12 (46.2%) | 0.063 | |
| 3 | 0 (0.0%) | 8 (10.8%) | 7 (11.1%) | 3 (5.0%) | 4 (6.7%) | 3 (5.4%) | 5 (19.2%) | |||
| 4 | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | |||
| Nonspecific activity in blood pool | 1 | 11 (16.9%) | 5 (6.8%) | 3 (4.8%) | 0.131 (C) | 2 (3.3%) | 5 (8.3%) | 6 (10.7%) | 6 (23.1%) | 0.021 (F) |
| 2 | 9 (13.9%) | 12 (16.2%) | 13 (20.6%) | 0.319 | 11 (18.3%) | 7 (11.7%) | 8 (14.3%) | 8 (30.8%) | 0.014 | |
| 3 | 45 (69.2%) | 57 (77.0%) | 47 (74.6%) | 47 (78.3%) | 48 (80.0%) | 42 (75.0%) | 12 (46.2%) | |||
| Bone/marrow | 2 | 44 (67.7%) | 51 (68.9%) | 44 (69.8%) | 0.641 (F) | 47 (78.3%) | 42 (70.0%) | 36 (64.3%) | 14 (53.8%) | 0.026 (F) |
| 3 | 20 (30.8%) | 19 (25.7%) | 15 (23.8%) | 0.947 | 12 (20.0%) | 16 (26.7%) | 19 (33.9%) | 7 (26.9%) | 0.011 | |
| 4 | 1 (1.5%) | 4 (5.4%) | 4 (6.4%) | 1 (1.7%) | 2 (3.3%) | 1 (1.8%) | 5 (19.2%) | |||
| Impact | Yes | 2 (3.1%) | 1 (1.4%) | 4 (6.3%) | 0.264 (F) | 0 (0.0%) | 1 (1.7%) | 4 (7.1%) | 2 (7.7%) | 0.051 (F) |
| No | 63 (96.9%) | 73 (98.6%) | 59 (93.7%) | 0.391 | 60 (100%) | 59 (98.3%) | 52 (92.9%) | 24 (92.3%) | 0.019 |
F = Fischer exact test and C = χ2 test; otherwise, P value is for Mantel-Haenszel test.